Psycho 576 (Cognitive Neuroscience): Human Neuroanatomy Through Cognitive Neuropsychology
Instructor: Chris Westbury
chrisw@ualberta.ca


W F 14:30-15:50 BS P224

Course description: Untangling the relation between human brain structure and cognitive function is one of the great challenges facing scientific psychology. In this seminar we will use human brain damage and brain-imaging data as a guide to understanding human functional neuroanatomy and the structure of human cognition. The focus will be on case studies that illustrate how human cognitive functions can break down following brain damage, with an emphasis on disorders of knowledge and understanding. A neuroanatomical or neuropsychological background is not an absolute requirement, but a willingness to learn to take a neurological perspective to psychological questions is. Students will each make at least one detailed class presentation, and write one analytical review paper on a relevant topic of their choice.

Lecture Schedule

        Please note that there will be no 576 class on

Wednesday October 9th, Wednesday November 20, or Friday November 22.

 

DATE

TOPIC

READING

Wednesday, September 4

Introduction to the class

No reading

Friday, September 6

Introduction to the human brain

The Architecture of the Brain- R. Ornstein & R. Thompson (1984). The Amazing Brain (Chapter 1), Boston: Houghton Mifflin. & Neuroscience Overview- P. Churchland & T. Sejnowski (1992). The Computational Brain (Chapter 2). Cambridge, MA: MIT Press.

Wednesday September 11

Computation & functionalism

Minds, brains, and programs- J. Searle (1980) Behavioral and Brain Sciences 3 (3):417-457

Friday September 13

Phenomenology and the binding problem

• Time and the observer: the Where and When of Consciousness in the Brain- D. Dennett & M. Kinsbourne (1992). Behavioral and Brain Sciences, 15, 183-247.

Wednesday September 18

Techniques I: Human lesion studies

Is cognitive neuropsychology possible?- A. Caramazza (1992). Journal of Cognitive Neuroscience, 4, 80-95. & Is cognitive neuropsychology plausible?- S. Kosslyn & J. Intriligator (1992). Journal of Cognitive Neuroscience, 4, 96-106.

Friday September 20

Techniques II: Functional brain imaging

Behind the scenes of functional imaging- A historical and physiological perspective- M. Raichle (1998). Proceedings of the National Academy of Science, 95:765-772

Wednesday September 25

Why do we like doing cross-word puzzles? (Dorsolateral pre-frontal cortex)

"Sculpting the Response Space"- An Account of Left Prefrontal Activation at Encoding- P. Fletcher, T. Shallice, & R.J. Dolan (2000).  Neuroimage, 12, 404-417.

Friday, September 27

Personality and frontal lobe functioning (Cingulate gyrus, Executive functions)

ļ Anatomical Variability of the Anterior Cingulate Gyrus and Basic Dimensions of Human Personality- J. Pujol, A. LŪpez, J. Deus, N. Cardoner, J. Vallejo, A. Capdevila, T. Paus (2002). NeuroImage, 15:4, 847-855

Wednesday October 2

When does our brain see? (Frontal eye fields)

Inverted vision after frontal lobe disease- M. Solms, K. Kaplan-Solms, M. Saling, & Percy M. (1988). Cortex, 24, 499-509.

Friday October 4

Our ever-changing brain (Cortical plasticity in sensory-motor cortex)

Large scale reorganization at multiple levels of the somatosensory pathway follows therapeutic amputation of the hand in monkeys- S. Florence & J. Hass (1995). The Journal Of Neuroscience, 15(12), 8083-8095.

Wednesday October 9

NO CLASS

NO CLASS

Friday October 11

Ignoring half the world (Hemi-neglect)

The Sound of One Hand Clapping- V. Ramachandran & S. Blakeslee (1998). Phantoms In the Brain (Chapter 7), New York: William Morrow

Wednesday October 16

The body has a mind of its own (Alien hand syndrome)

Two alien hand syndromes- T. Feinberg, R. Schindler, N. Flanagan, L. Haber (1992). Neurology, 42, 19-24.

Friday October 18

Class cancelled due to lack of quorum.

Wednesday October 23

Learned movement disorders (Ideomotor apraxia)

Neuropsychological and neuroanatomical dimensions of ideomotor apraxia- M. Alexander, E. Baker, M. Naeser, E. Kaplan, & C. Plumbo (1992). Brain, 115, 87-107

Friday October 25

An odd Grundst–rung (Gerstmann's syndrome)

A pure case of Gerstmann syndrome with a subangular lesion- E. Mayer, M-D. Martory, A. Pegna, T. Landis, J. Delavelle, and J-M Annoni (1999). Brain 122: 1107-1120

Wednesday October 30

Play it again (Music agnosia)

Music Agnosias: Selective Impairment of Music Recognition after Brain Damage-  S. Dalla Bella & I. Peretz (1999). Journal of New Music Research, 28, 209-216.

Friday November 1

The man who mistook his strawberry for a pear (Category-specific agnosia)

Shape integration for visual object recognition and its implication in category-specific agnosia- M. Arguin, D. Bub, & G. Dudek (1996). Visual Cognition, 3(3):221-275.

Wednesday November 6

Who do you know? Who do you love? (Prosopagnosia  & Capgras Syndrome)

Prosopagnosia: anatomic basis and behavioral mechanisms- A. Damasio, H. Damasio, & G. Can Hoesen (1982). Neurology, 32, 331-341. & Edelstyn, N. & Oyebode, F. (1999). A review of the phenomenology & cognitive neuropsychological origins of Capgras Syndrome. International Journal of Geriatric Psychiatry, 14, 48-59.

Friday November 8

I don't believe my eyes (Blindsight & Blindness denial)

Blindsight in man and monkey- Stoerig, P. & Cowey, A. (1997). Brain, 120, 535:559.

Wednesday November 13

I don't see it that way (Motion & Color Blindness)

Cerebral akinetopsia (Visual motion blindness): A Review- S. Zeki (1991). Brain, 114, 811-824.

Friday November 15

Seeing is not always believing (Visual hallucinations)

Complex visual hallucinations: Clinical and neurobiological insights- Manford, M. & Andermann, F. (1998). Brain, 121: 1819-1840.

Wednesday November 20

NO CLASS

NO CLASS

Friday November 22

NO CLASS

NO CLASS

Wednesday November 27

I don't believe my ears (Deaf hearing)

The neural correlates of 'deaf-hearing' in man- A Engelien et al. (2000). Brain, 123:532-545 [or, a student presentation]

Friday November 29

Class moved- see below

 

Tuesday December 3 @ 4 PM

A cognitive heresy: Why I don't believe we process symbols

Some assembled reminders on the triadic structure of the symbol

Optional additional and equally odd reading: www.psycho-ontology.net

Wednesday December 4

General discussion & optional field visit to study the phenomenology of alcohol.

 

Introductory Neuropsychology course taught in the Department of Clinical & Health Psychology of MCP Hahnemann University.

Mammalian Brain Museum from the University of Wisconsin and Michigan State Comparative Mammalian Brain Collections

The Whole Brain Atlas at Harvard University